7679/10 | Tocris Bioscience 7679/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7679/10

catalog :

7679/10

quantity :

10 mg (also 50 mg)

price :

181 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7679 - RECTAS C10H8ClN5O CAS No. 101862-47-9

product information

master code :

7679

SKU :

7679/10

product name :

RECTAS

unit size :

10 mg (also 50 mg)

description :

IKBKAP pre-mRNA splicing modulator

target :

DNA, RNA and Protein Synthesis Compounds

category :

Small Molecules

purity :

98%

observed molecular weight :

249.66

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

RECTAS (rectifier of aberrant splicing) is a pre-mRNA splicing modulator of the IKBKAP (inhibitor of light polypeptide gene enhancer in B-cells, kinase complex associated protein) gene. It corrects aberrant IKBKAP splicing in vitro in cellular models of familial dysautonomia and in vivo in transgenic mice. In combination with Phenylbutyric acid (Cat. No. 2682), RECTAS rescues PARK7 aberrant splicing and neuronal cell loss in a midbrain organoid model of familial Parkinson s disease. Orally bioavailable and brain penetrant.

top caption :

IKBKAP pre-mRNA splicing modulator

extended description :

IKBKAP pre-mRNA splicing modulator

chemical name text :

2-Chloro-N-(2-furanylmethyl)-7H-purin-6-amine

formula :

C10H8ClN5O

formula text :

C10H8ClN5O

cas num :

101862-47-9

USD :

181 USD

product details :

IKBKAP pre-mRNA splicing modulator

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage