7678/100 | Tocris Bioscience 7678/100 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7678/100

catalog :

7678/100

quantity :

100 mg

price :

325 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7678 - 5-Amino-Thalidomide C13H11N3O4 CAS No. 191732-76-0

product information

master code :

7678

SKU :

7678/100

product name :

5-Amino-Thalidomide

unit size :

100 mg

description :

Cereblon ligand with amine on C5 for onward chemistry

target :

Degrader Building Blocks

category :

Small Molecules

purity :

95%

observed molecular weight :

273.24

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

5-Amino-Thalidomide is a functionalized cereblon (CRBN) ligand for PROTAC research and development; incorporates an E3 ligase ligand with an amine on the C5 position of the phthalimide ring for onward chemistry to generate Protein Degraders with rigid linkers. Degraders with modifications on the C5 position reduce off-target zinc-finger proteins degradation. . Part of a range of functionalized tool molecules for PROTAC Degrader R D. . Please contact us for SD files of our available Degrader Building Blocks. . PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

top caption :

Cereblon ligand with amine on C5 for onward chemistry

extended description :

Cereblon ligand with amine on C5 for onward chemistry

chemical name text :

5-Amino-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione

formula :

C13H11N3O4

formula text :

C13H11N3O4

cas num :

191732-76-0

USD :

325 USD

product details :

Cereblon ligand with amine on C5 for onward chemistry

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage