7651/5 | Tocris Bioscience 7651/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7651/5

catalog :

7651/5

quantity :

5 mg

price :

386 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7651 - PT-65 C51H63N13O12S CAS No. 2721998-87-2

product information

master code :

7651

SKU :

7651/5

product name :

PT-65

unit size :

5 mg

description :

Potent GSK3 Degrader (PROTAC )

target :

Active Degraders

category :

Small Molecules

purity :

98%

observed molecular weight :

1082.19

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PT-65 is a potent GSK3 Degrader (PROTAC ) (DC50 = 28.3 nM and 34.2 nM against GSK3 and GSK3 , respectively, in SH-SY5Y cells). It suppresses Okadaic acid (Cat. No. 1136) -induced tau hyperphosphorylation and ameliorates learning and memory impairments in rat models of Alzheimer s disease. . GSK3 antibodies validated for Western Blot also available: Catalog # NBP1-47470 and AF2157 . . PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license .

top caption :

Potent GSK3 Degrader (PROTAC )

extended description :

Potent GSK3 Degrader (PROTAC )

chemical name text :

3-Amino-6-(4-((4-(4-(1-(17-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12,15-pentaoxaheptadecyl)-1H-1,2,3-triazol-4-yl)butyl)piperazin-1-yl)sulfonyl)phenyl)-N-(pyridin-3-yl)pyrazine-2-carboxamide

formula :

C51H63N13O12S

formula text :

C51H63N13O12S

cas num :

2721998-87-2

USD :

386 USD

product details :

Potent GSK3 Degrader (PROTAC )

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage