7650/10 | Tocris Bioscience 7650/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7650/10

catalog :

7650/10

quantity :

10 mg (also 50 mg)

price :

223 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7650 - AZD 2858 C21H23N7O3S CAS No. 486424-20-8

product information

master code :

7650

SKU :

7650/10

product name :

AZD 2858

unit size :

10 mg (also 50 mg)

description :

Highly potent GSK-3 inhibitor; inhibits tau phosphorylation

target :

Glycogen Synthase Kinase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

453.52

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

AZD 2858 is a potent glycogen synthase kinase-3 (GSK-3) inhibitor (IC50 values are 0.9 and 5 nM for GSK-3 and GSK-3 , respectively). AZD 2858 inhibits tau phosphorylation in vitro (IC50 = 76 nM), improves fracture healing and increases bone mass in rodent models of bone fracture. Also activates Wnt signaling in vitro and in vivo . Brain permeable and orally bioavailable.

top caption :

Highly potent GSK-3 inhibitor; inhibits tau phosphorylation

extended description :

Highly potent GSK-3 inhibitor; inhibits tau phosphorylation

chemical name text :

3-Amino-6-[4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-N-3-pyridinyl-2-pyrazinecarboxamide

formula :

C21H23N7O3S

formula text :

C21H23N7O3S

cas num :

486424-20-8

USD :

223 USD

product details :

Highly potent GSK-3 inhibitor; inhibits tau phosphorylation

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage