7635/50U | Tocris Bioscience 7635/50U product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7635/50U

catalog :

7635/50U

quantity :

50 ug

price :

820 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7635 - tri-GalNAc biotin C83H146N14O34S

product information

master code :

7635

SKU :

7635/50U

product name :

tri-GalNAc biotin

unit size :

50 ug

description :

Biotinylated ASGPR ligand for LYTAC research and development

target :

Degrader Building Blocks

category :

Small Molecules

purity :

90%

observed molecular weight :

1916.21

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Tri-GalNAc-biotin is a biotinylated asialoglycoprotein receptor (ASGPR) ligand for lysosomal targeting chimera (LYTAC) research and development, comprising a triantennary N -acetylgalactosamine (GalNAc) joined by a PEG linker to biotin. Tri-GalNAc-biotin can induce ASGPR-mediated endocytosis and trafficking of fluorescently labeled neutravidin for lysosomal degradation in HepG2 cells in a time-dependent manner. The increase in fluorescent signal within cells plateaus after 16-20h, and this effect can be inhibited by addition of tri-GalNAc COOH (Cat. No. 7401).

top caption :

Biotinylated ASGPR ligand for LYTAC research and development

extended description :

Biotinylated ASGPR ligand for LYTAC research and development

formula :

C83H146N14O34S

formula text :

C83H146N14O34S

USD :

820 USD

product details :

Biotinylated ASGPR ligand for LYTAC research and development

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage