product summary
Loading...
company name :
Tocris Bioscience
product type :
chemical
product name :
7634/100
catalog :
7634/100
quantity :
100 mg
price :
505 USD
more info or order :
image
image 1 :
Tocris Bioscience 7634/100 image 1
Me VH 032, amine CAS No. 2504950-56-3 Amine functionalized VHL ligand for PROTAC research
product information
master code :
7634
SKU :
7634/100
product name :
Me VH 032, amine
unit size :
100 mg
description :
Amine functionalized VHL ligand for PROTAC research
target :
Degrader Building Blocks
category :
Small Molecules
purity :
95%
observed molecular weight :
517.51
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Me VH 032, amine is a derivative of the von Hippel-Lindau (VHL) ligand, VH 032 for use as a precursor to a PROTAC that hijacks VHL as the E3 ubiquitin ligase component. Me VH 032, amine is supplied with a primary amine functional handle, for ready conjugation to a linker/target protein ligand. Introduction of the methyl group at the benzylic position of VH 032 is associated with improved binding affinity. . Please contact us for SD files of our available Degrader Building Blocks. . PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license. . Require a different derivative? Get in touch
top caption :
Amine functionalized VHL ligand for PROTAC research
extended description :
Amine functionalized VHL ligand for PROTAC research
chemical name text :
(4R)-3-Methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-L-prolinamide dihydrochloride
formula :
C23H32N4O3S.2HCl
formula text :
C23H32N4O3S.2HCl
cas num :
2504950-56-3
USD :
505 USD
product details :
Amine functionalized VHL ligand for PROTAC research
storage :
Desiccate at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK