3-Mercaptopicolinic acid hydrochloride | Tocris Bioscience 7577/50 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

3-Mercaptopicolinic acid hydrochloride

catalog :

7577/50

quantity :

50 mg

price :

67 USD

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

7577

SKU :

7577/50

product name :

3-Mercaptopicolinic acid hydrochloride

description :

Phospoenolpyruvate carboxykinase (PEPCK) inhibitor; inhibits gluconeogenesis

target :

PCK1

unit size :

50 mg

category :

Small Molecules

storage :

Store at -20°C

observed molecular weight :

191.63

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

3-Mercaptopicolinic acid hydrochloride is a phospoenolpyruvate carboxykinase (PEPCK) inhibitor (IC50 = 7.5 M at hPEPCK). Inhibits glucose synthesis. In vitro , 3-Mercaptopicolinic acid reduces proliferation of Treg cells, induces myogenic differentiation of C2C12 cells, and reduces colony growth formation of MCF7 cells. Also sensitizes melanoma cells to Vemurafenib (Cat. No. 7309) via inhibition of cytoplasmic PEPCK.

product keywords :

3MP 3mercaptopicolinic acid mercaptopicolinic PEPCK PCK1 inhibitors glucose synthesis T cells proliferation myogenic differentiation colony growth formation melanoma phosphoenolpyruvate carboxykinase Other Lyases Other Differentiation Products 7577, PCK 1, PEPCK C, Phosphoenolpyruvate carboxylase, PEP carboxykinase, Phosphoenolpyruvate Carboxykinase 1, gluconeogenesis

extended description :

Phospoenolpyruvate carboxykinase (PEPCK) inhibitor; inhibits gluconeogenesis

chemical name text :

3-Mercapto-2-pyridinecarboxylic acid hydrochloride

formula :

C6H5NO2S.HCl

formula text :

C6H5NO2S.HCl

cas num :

320386-54-7

USD :

USD 2025 :

67 USD

product details :

Phospoenolpyruvate carboxykinase (PEPCK) inhibitor; inhibits gluconeogenesis

alt names :

EC 4.1.1.32, MGC22652, PEPCK1, PEPCKC, PEPCK-C, PEPCK-CPEP carboxykinase, phosphoenolpyruvate carboxykinase 1 (soluble), phosphoenolpyruvate carboxykinase, cytosolic, phosphoenolpyruvate carboxykinase, cytosolic [GTP], Phosphoenolpyruvate carboxylase, phosphopyruvate carboxylase