7570/10 | Tocris Bioscience 7570/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7570/10

catalog :

7570/10

quantity :

10 mg (also 50 mg)

price :

275 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Potent and selective pan-CLK inhibitor; also inhibits DYRK1A/B

product information

master code :

7570

SKU :

7570/10

product name :

T3 CLK

unit size :

10 mg (also 50 mg)

description :

Potent and selective pan-CLK inhibitor; also inhibits DYRK1A/B

target :

Cdc2-like Kinase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

482.58

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

T3 CLK is a potent and selective pan CDC-like kinase (CLK) inhibitor (IC50 values are 0.67 nM, 15 nM, and 110 nM for CLK1, CLK2, and CLK3 protein kinases, respectively). T3 CLK also inhibits DYRK1A/B (IC50 values are 230 nM and 260 nM for DYRK1B and DYRK1A, respectively in cellular assays). Exhibits dose-dependent alternative splicing effects in HCT116 colorectal cancer cells. T3 CLK is cell permeable, stable and non-toxic.

top caption :

Potent and selective pan-CLK inhibitor; also inhibits DYRK1A/B

extended description :

Potent and selective pan-CLK inhibitor; also inhibits DYRK1A/B

chemical name text :

4-[1,1-Dimethyl-2-(4-methyl-1-piperazinyl)-2-oxoethyl]-N-[6-(4-pyridinyl)imidazo[1,2-a]pyridin-2-yl]benzamide

formula :

C28H30N6O2

formula text :

C28H30N6O2

cas num :

2109805-56-1

USD :

275 USD

product details :

Potent and selective pan-CLK inhibitor; also inhibits DYRK1A/B

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage