7561/10 | Tocris Bioscience 7561/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7561/10

catalog :

7561/10

quantity :

10 mg

price :

191 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

G6PDi 1 CAS No. 2457232-14-1 Potent, reversible glucose-6-phosphate dehydrogenase (G6PD) inhibitor

product information

master code :

7561

SKU :

7561/10

product name :

G6PDi 1

unit size :

10 mg

description :

Potent, reversible glucose-6-phosphate dehydrogenase (G6PD) inhibitor

target :

G6PD

category :

Small Molecules

purity :

98%

observed molecular weight :

284.34

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

G6PDi 1 is a potent, reversible, nonsteroidal inhibitor of glucose-6-phosphate dehydrogenase (G6PD) (IC50 = 70 nM. The compound dose-dependently and reversibly decreases 6-phosphogluconolactone (6-PG) levels in HCT116 and HepG2 cell lines in vitro . In activated T cells, G6PDi-1 inhibits flux through the pentose phosphate pathway and decreases NADPH generation. It also inhibits production of cytokines by activated T cells and oxidative burst in neutrophils.

top caption :

Potent, reversible glucose-6-phosphate dehydrogenase (G6PD) inhibitor

extended description :

Potent, reversible glucose-6-phosphate dehydrogenase (G6PD) inhibitor

chemical name text :

4-((5-Oxo-6,7,8,9-tetrahydro-5H-cyclohepta[d]pyrimidin-2-yl)amino)thiophene-2-carbonitrile

formula :

C14H12N4OS

formula text :

C14H12N4OS

cas num :

2457232-14-1

USD :

191 USD

product details :

Potent, reversible glucose-6-phosphate dehydrogenase (G6PD) inhibitor

alt names :

G6PD, G6PD1EC 1.1.1.49, G6PDH, glucose-6-phosphate dehydrogenase

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage