product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
7558/10
catalog :
7558/10
quantity :
10 mg (also 50 mg)
price :
177 USD
more info or order :
image
image 1 :
Tocris Bioscience 7558/10 image 1
Cat.No. 7558 - SRT 1720 C25H23N7OS CAS No. 925434-55-5
product information
master code :
7558
SKU :
7558/10
product name :
SRT 1720
unit size :
10 mg (also 50 mg)
description :
Selective SIRT1 activator; induces autophagy and mitochondrial biogenesis
target :
Sirtuin 1/SIRT1
category :
Small Molecules
purity :
98%
observed molecular weight :
469.56
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
SRT 1720 is selective SIRT 1 activator (EC50 = 0.16 M). SRT 1720 inhibits growth of bladder cancer organoids and xenografts (IC50 = 0.35 M) and induces autophagy. In vitro , SRT 1720 increases mitochondrial biogenesis and recovery after oxidation injury and reduces palmitate-induced insulin resistance. Also improves survival and healthspan of obese mice.
top caption :
Selective SIRT1 activator; induces autophagy and mitochondrial biogenesis
extended description :
Selective SIRT1 activator; induces autophagy and mitochondrial biogenesis
chemical name text :
N-[2-[3-(1-Piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-2-quinoxalinecarboxamide
formula :
C25H23N7OS
formula text :
C25H23N7OS
cas num :
925434-55-5
USD :
177 USD
product details :
Selective SIRT1 activator; induces autophagy and mitochondrial biogenesis
alt names :
EC 3.5.1, S. cerevisiae, homolog) 1, SIR2alpha, SIR2L1, SIR2-like protein 1, SIRT1, sirtuin 1
storage :
Store at -20░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK