7549/10 | Tocris Bioscience 7549/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7549/10

catalog :

7549/10

quantity :

10 mg

price :

252 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7549 - BAY 1816032 C27H24F2N6O4 CAS No. 1891087-61-8

product information

master code :

7549

SKU :

7549/10

product name :

BAY 1816032

unit size :

10 mg

description :

Potent and selective BUB1 kinase inhibitor

target :

Checkpoint Control Kinase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

534.52

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

BAY 1816032 is a potent and selective inhibitor of BUB1 kinase, a mitotic checkpoint serine/threonine kinase (IC50 = 6.1 nM). BAY 1816032 shows 17-fold selectivity over a panel of 403 other human kinases. In vivo , BAY 1816032 decreases tumor size in tumor xenograft models. BAY 181603 is orally bioavailable.

top caption :

Potent and selective BUB1 kinase inhibitor

extended description :

Potent and selective BUB1 kinase inhibitor

chemical name text :

2-[3,5-Difluoro-4-[[3-[5-methoxy-4-[(3-methoxy-4-pyridinyl)amino]-2-pyrimidinyl]-1H-indazol-1-yl]methyl]phenoxy]ethanol

formula :

C27H24F2N6O4

formula text :

C27H24F2N6O4

cas num :

1891087-61-8

USD :

252 USD

product details :

Potent and selective BUB1 kinase inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage