7503/5 | Tocris Bioscience 7503/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7503/5

catalog :

7503/5

quantity :

5 mg

price :

413 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7503 - MD13 C35H35N5O8

product information

master code :

7503

SKU :

7503/5

product name :

MD13

unit size :

5 mg

description :

Potent MIF Degrader (PROTAC )

target :

Active Degraders

category :

Small Molecules

purity :

98%

observed molecular weight :

653.69

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

MD13 is a potent macrophage migration inhibitory factor (MIF) Degrader (PROTAC DC50 100 nM; Dmax = 92% after 6 h). MD13 comprises the cereblon ligand Pomalidomide (Cat. No. 6302) joined by a linker to a MIF inhibitor. MD13 reduces MIF levels, arrests cells at the G2/M phase and inhibits proliferation of A549 lung carcinoma cells. Growth of A549 cell 3D spheroids is also inhibited by MD13. . Negative control MD15 (Cat. No. 7504) and MIF antibodies validated for Simple Western (automated Western) instruments and Western Blot also available: Catalog # AF-289-PB and MAB289 . . PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

top caption :

Potent MIF Degrader (PROTAC )

extended description :

Potent MIF Degrader (PROTAC )

chemical name text :

8-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-N-(4-(7-hydroxy-2-oxo-2H-benzo[e][1,3]oxazin-3(4H)-yl)phenyl)octanamide

formula :

C35H35N5O8

formula text :

C35H35N5O8

cas num :

2758431-97-7

USD :

413 USD

product details :

Potent MIF Degrader (PROTAC )

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage