7498/10 | Tocris Bioscience 7498/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7498/10

catalog :

7498/10

quantity :

10 mg

price :

285 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7498 - SPOP-i-6lc C26H31N7O2S CAS No. 2136270-56-7

product information

master code :

7498

SKU :

7498/10

product name :

SPOP-i-6lc

unit size :

10 mg

description :

SPOP E3 ubiquitin ligase inhibitor

target :

Ubiquitin Ligase (E3) Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

505.64

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

SPOP-i-6lc is a selective SPOP E3 ubiquitin ligase inhibitor (IC50 = 2.1 M and 3.5 M, in A498 and OS-RC-2 cell lines, respectively). In vitro , SPOP-i-6lc suppresses viability and proliferation of A498 and OS-RC-2 kidney cancer cell lines. SPOP-i-6lc leads to the accumulation of tumor suppressors PTEN and DUSP7 and decreased levels of phosphorylated AKT and ERK in clear-cell renal cell carcinoma (ccRCC) cell lines.

top caption :

SPOP E3 ubiquitin ligase inhibitor

extended description :

SPOP E3 ubiquitin ligase inhibitor

chemical name text :

1,5-Dihydro-2-imino-10-methyl-N-[2-(4-methyl-1-piperazinyl)ethyl]-5-oxo-1-[2-(2-thienyl)ethyl]-2H-dipyrido[1,2-a:2 ,3 -d]pyrimidine-3-carboxamide

formula :

C26H31N7O2S

formula text :

C26H31N7O2S

cas num :

2136270-56-7

USD :

285 USD

product details :

SPOP E3 ubiquitin ligase inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage