7497/10 | Tocris Bioscience 7497/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7497/10

catalog :

7497/10

quantity :

10 mg (also 50 mg)

price :

131 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7497 - Vandetanib C22H24BrFN4O2 CAS No. 443913-73-3

product information

master code :

7497

SKU :

7497/10

product name :

Vandetanib

unit size :

10 mg (also 50 mg)

description :

Potent VEGFR-2 inhibitor, also inhibits EGFR and RET oncoproteins activity

target :

VEGF Receptor Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

475.36

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Vandetanib is a potent VEGFR-2 inhibitor (IC50 = 0.04 M), and inhibitor of EGFR (IC50 = 0.5 M). Vandetanib potently inhibits (IC50 = 100 nM) RET oncoprotein activity in human thyroid cancer. Vandetanib displays anti-angiogenic properties in human nasopharyngeal carcinoma in mice model. Vandetanib is orally available and effective in vivo .

top caption :

Potent VEGFR-2 inhibitor, also inhibits EGFR and RET oncoproteins activity

extended description :

Potent VEGFR-2 inhibitor, also inhibits EGFR and RET oncoproteins activity

chemical name text :

N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine

formula :

C22H24BrFN4O2

formula text :

C22H24BrFN4O2

cas num :

443913-73-3

USD :

131 USD

product details :

Potent VEGFR-2 inhibitor, also inhibits EGFR and RET oncoproteins activity

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage