7492/10 | Tocris Bioscience 7492/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7492/10

catalog :

7492/10

quantity :

10 mg (also 50 mg)

price :

193 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7492 - Lomitapide mesylate C39H37F6N3O2.CH3SO3H CAS No. 2059395-52-5

product information

master code :

7492

SKU :

7492/10

product name :

Lomitapide mesylate

unit size :

10 mg (also 50 mg)

description :

Potent microsomal triglyceride transfer protein (MTP) inhibitor

target :

Lipid Metabolism Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

789.83

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Lomitapide mesylate is a potent inhibitor of microsomal triglyceride transfer protein (IC50 = 8 nM). Lomitapide inhibits or normalizes lipoprotein production in rodents and in a rabbit model of hypercholesterolemia. Lomitapide is antimalarial; it inhibits hemozoin formation and growth of CQ-sensitive ( Pf NF54) and multidrug-resistant ( Pf K1) strains of P. falciparum (IC50 values are 0.56 uM and 0.69 uM respectively). Orally bioavailable.

top caption :

Potent microsomal triglyceride transfer protein (MTP) inhibitor

extended description :

Potent microsomal triglyceride transfer protein (MTP) inhibitor

chemical name text :

N-(2,2,2-Trifluoroethyl)-9-[4-[4-[[[4 -(trifluoromethyl)[1,1 -biphenyl]-2-yl]carbonyl]amino]-1-piperidinyl]butyl]-9H-fluorene-9-carboxamide methanesulfonate

formula :

C39H37F6N3O2.CH3SO3H

formula text :

C39H37F6N3O2.CH3SO3H

cas num :

2059395-52-5

USD :

193 USD

product details :

Potent microsomal triglyceride transfer protein (MTP) inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage