product summary
Loading...
company name :
Tocris Bioscience
product type :
chemical
product name :
7485/10
catalog :
7485/10
quantity :
10 mg (also 50 mg)
price :
142 USD
more info or order :
image
image 1 :
Tocris Bioscience 7485/10 image 1
Cat.No. 7485 - Covidcil-19 C16H14N4O2 CAS No. 1225177-95-6
product information
master code :
7485
SKU :
7485/10
product name :
Covidcil-19
unit size :
10 mg (also 50 mg)
description :
Binds to SARS-CoV-2 frameshifting element and reduces frameshifting efficiency
target :
Antiviral Compounds
category :
Small Molecules
purity :
98%
observed molecular weight :
294.31
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Covidcil-19 binds to the revised attenuator hairpin structure of the SARS-CoV-2 frameshifting element (FSE) with high affinity (Kd = 11 nM). It stabilizes the hairpin s folded state and reduces frameshifting efficiency in cells. Covidcil-19 inhibits viral propagation and reduces viral infectivity by 3.5 orders of magnitude.
top caption :
Binds to SARS-CoV-2 frameshifting element and reduces frameshifting efficiency
extended description :
Binds to SARS-CoV-2 frameshifting element and reduces frameshifting efficiency
chemical name text :
3-[[4-(Methylamino)-2-quinazolinyl]amino]benzoic acid
formula :
C16H14N4O2
formula text :
C16H14N4O2
cas num :
1225177-95-6
USD :
142 USD
product details :
Binds to SARS-CoV-2 frameshifting element and reduces frameshifting efficiency
storage :
Store at -20░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK