7476/5 | Tocris Bioscience 7476/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7476/5

catalog :

7476/5

quantity :

5 mg (also 25 mg)

price :

116 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Covalent RNF114 ligand

product information

master code :

7476

SKU :

7476/5

product name :

EN 219

unit size :

5 mg (also 25 mg)

description :

Covalent RNF114 ligand

target :

RNF114

category :

Small Molecules

purity :

98%

observed molecular weight :

456.56

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

EN 219 is a covalent RNF114 inhibitor (IC50 = 470 nM). In vitro EN 219 mimics the mechanism of action of Nimbolide (Cat. No. 7289) by binding to RNF114 and inhibiting ubiquitination of its endogenous substrate, the tumor suppressor p21.

top caption :

Covalent RNF114 ligand

extended description :

Covalent RNF114 ligand

chemical name text :

1-[3,5-bis(4-Bromophenyl)-4,5-dihydro-1H-pyrazol-1-yl]-2-chloroethanone

formula :

C17H13Br2ClN2O

formula text :

C17H13Br2ClN2O

cas num :

380351-29-1

USD :

116 USD

product details :

Covalent RNF114 ligand

alt names :

CDKN1A, CIP1, PSORS12, ZNF228, ZNF313

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage