7474/10 | Tocris Bioscience 7474/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7474/10

catalog :

7474/10

quantity :

10 mg (also 50 mg)

price :

160 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7474 - EN6 C19H14F2N4O2 CAS No. 1808714-73-9

product information

master code :

7474

SKU :

7474/10

product name :

EN6

unit size :

10 mg (also 50 mg)

description :

H+-ATPase activator; activates autophagy; inactivates mTORC1 signaling

target :

H+-ATPase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

368.34

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

EN6 is an activator of lysosomal vacuolar H+ ATPase (v-ATPase). EN6 covalently binds to the catalytic subunit of v-ATPase leading to increased acidification of lysosomes, inactivation of mTORC1 signaling and activation of autophagy in vivo . EN6 triggers entosis and promotes clearance of TDP43 protein aggregates in vitro .

top caption :

H+-ATPase activator; activates autophagy; inactivates mTORC1 signaling

extended description :

H+-ATPase activator; activates autophagy; inactivates mTORC1 signaling

chemical name text :

N-[4-Fluoro-3-[(1-oxo-2-propen-1-yl)amino]phenyl]-1-(2-fluorophenyl)-1H-pyrazole-4-carboxamide

formula :

C19H14F2N4O2

formula text :

C19H14F2N4O2

cas num :

1808714-73-9

USD :

160 USD

product details :

H+-ATPase activator; activates autophagy; inactivates mTORC1 signaling

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage