product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
7462/10
catalog :
7462/10
quantity :
10 mg
price :
160 USD
more info or order :
image
image 1 :
Tocris Bioscience 7462/10 image 1
Cat.No. 7462 - ET 18-OCH3 C27H58NO6P CAS No. 70641-51-9
product information
master code :
7462
SKU :
7462/10
product name :
ET 18-OCH3
unit size :
10 mg
description :
Selective PI-PLC inhibitor, also PAF receptor agonist
target :
Phospholipase C Inhibitors
category :
Small Molecules
observed molecular weight :
523.73
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
ET 18-OCH3 is a synthetic lysophospholipid analog that selectively inhibits phosphatidylinositol phospholipase C (IC50 = 9.6 M in fibroblasts and adenocarcinoma cells). ET 18-OCH3 acts as an agonist at platelet-activating factor (PAF) receptors. ET 18-OCH3 is an antitumor lipid that selectively induces apoptosis in tumor cells, sparing normal cells, and activates the intracellular Fas/CD95 death receptor. ETH 18-OCH3 also triggers eryptosis and interacts with mitochondrial membranes to increase mitochondrial membrane permeability, leading to dysfunction and apoptosis. Racemic mixture.
top caption :
Selective PI-PLC inhibitor, also PAF receptor agonist
extended description :
Selective PI-PLC inhibitor, also PAF receptor agonist
chemical name text :
4-Hydroxy-7-methoxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphaheptacosan-1-aminium 4-oxide
formula :
C27H58NO6P
formula text :
C27H58NO6P
cas num :
70641-51-9
USD :
160 USD
product details :
Selective PI-PLC inhibitor, also PAF receptor agonist
storage :
Store at -20░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK