7460/10 | Tocris Bioscience 7460/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7460/10

catalog :

7460/10

quantity :

10 mg (also 50 mg)

price :

144 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7460 - SGC SMARCA-BRDVIII C19H25N5O3 CAS No. 1997319-84-2

product information

master code :

7460

SKU :

7460/10

product name :

SGC SMARCA-BRDVIII

unit size :

10 mg (also 50 mg)

description :

Potent and selective SMARCA2/4 and PB1(bromo 5)-selective SWI/SNF bromodomain inhibitor

target :

Bromodomain Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

371.44

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

SGC-SMARCA-BRDVIII is a selective and high affinity SMARCA2/4 and PB1(bromo 5)-selective SWI/SNF bromodomains inhibitor (Kd(ITC) values are 35, 36 and 13 nM, respectively). SGC-SMARCA-BRDVIII exhibits selectivity over 25 other bromodomain families and shows no off-target activity on 85 protein kinases screened using temperature-shift binding assays. SGC-SMARCA-BRDVIII suppresses formation of 3T3-L1 mouse fibroblasts into adipocytes (EC50 1.0 M).

top caption :

Potent and selective SMARCA2/4 and PB1(bromo 5)-selective SWI/SNF bromodomain inhibitor

extended description :

Potent and selective SMARCA2/4 and PB1(bromo 5)-selective SWI/SNF bromodomain inhibitor

chemical name text :

1,1-Dimethylethyl 4-[3-amino-6-(2-hydroxyphenyl)-4-pyridazinyl]-1-piperazinecarboxylate bromodomains

formula :

C19H25N5O3

formula text :

C19H25N5O3

cas num :

1997319-84-2

USD :

144 USD

product details :

Potent and selective SMARCA2/4 and PB1(bromo 5)-selective SWI/SNF bromodomain inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage