7450/10 | Tocris Bioscience 7450/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7450/10

catalog :

7450/10

quantity :

10 mg (also 50 mg)

price :

163 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Di Lorenzo G, Iavarone F, Maddaluno M, Plata G xf3 mez A, Aureli S, Quezada Meza C, et al. Phosphorylation of FAM134C by CK2 controls starvation-induced ER-phagy. Sci Adv. 2022;8:eabo1215 pubmed publisher

image

image 1 :

Cat.No. 7450 - SGC CK2-1 C20H21N7O CAS No. 2470424-39-4

product information

master code :

7450

SKU :

7450/10

product name :

SGC CK2-1

unit size :

10 mg (also 50 mg)

description :

Potent CK2A2 and CK2A1 inhibitor; also inhibits DYRK2

target :

Casein Kinase 2 Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

375.44

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

SGC CK2-1 is a potent inhibitor of casein kinase 2 (CK2) with activity at both the CK2A2 and CK2A1 isoforms (IC50 values are 2.3-16 nM and 4.2-36 nM respectively). SGC CK-1 also inhibits DYRK2 (IC50 = 440 nM).

top caption :

Potent CK2A2 and CK2A1 inhibitor; also inhibits DYRK2

extended description :

Potent CK2A2 and CK2A1 inhibitor; also inhibits DYRK2

chemical name text :

N-[5-[[3-Cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-methylphenyl]propanamide

formula :

C20H21N7O

formula text :

C20H21N7O

cas num :

2470424-39-4

USD :

163 USD

product details :

Potent CK2A2 and CK2A1 inhibitor; also inhibits DYRK2

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage