7445/10 | Tocris Bioscience 7445/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7445/10

catalog :

7445/10

quantity :

10 mg (also 50 mg)

price :

109 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7445 - GPR52 Comp-43 C15H14OS CAS No. 1239987-91-7

product information

master code :

7445

SKU :

7445/10

product name :

GPR52 Comp-43

unit size :

10 mg (also 50 mg)

description :

GPR52 receptor antagonist

target :

Orphan 7-TM Receptor Antagonists

category :

Small Molecules

purity :

98%

observed molecular weight :

242.34

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

GPR52 Comp-43 is a GPR52 receptor antagonist (IC50 = 0.63 M). The use of GPR52 Comp-43 in animal models of Huntington s Disease leads to degradation and reduction of soluble and aggregated mutant huntingtin protein in the striatum. It also reduces neuronal loss, promotes neuronal survival and improves motor functions in vivo . GPR52 Comp-43 is active in vitro and brain penetrant.

top caption :

GPR52 receptor antagonist

extended description :

GPR52 receptor antagonist

chemical name text :

(2E)-5-Phenyl-1-(2-thienyl)-2-penten-1-one

formula :

C15H14OS

formula text :

C15H14OS

cas num :

1239987-91-7

USD :

109 USD

product details :

GPR52 receptor antagonist

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage