7441/25 | Tocris Bioscience 7441/25 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7441/25

catalog :

7441/25

quantity :

25 mg

price :

199 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Kalasová I, Hailstone R, Bublitz J, Bogantes J, Hofmann W, Leal A, et al. Pathological mutations in PNKP trigger defects in DNA single-strand break repair but not DNA double-strand break repair. Nucleic Acids Res. 2020;48:6672-6684 pubmed publisher
Calo E, Gu B, Bowen M, Aryan F, Zalc A, Liang J, et al. Tissue-selective effects of nucleolar stress and rDNA damage in developmental disorders. Nature. 2018;554:112-117 pubmed publisher

image

image 1 :

Cat.No. 7441 - Pomalidomide 4 -alkylC4-azide C17H18N6O4

product information

master code :

7441

SKU :

7441/25

product name :

Pomalidomide 4'-alkylC4-azide

unit size :

25 mg

description :

Cereblon ligand with alkyl linker and terminal azide for onward chemistry

target :

Degrader Building Blocks

category :

Small Molecules

purity :

95%

observed molecular weight :

370.37

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Pomalidomide 4 -alkylC4-azide is a functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC4 linker with terminal azide ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R D. . Please contact us for SD files of our available Degrader Building Blocks. . PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

top caption :

Cereblon ligand with alkyl linker and terminal azide for onward chemistry

extended description :

Cereblon ligand with alkyl linker and terminal azide for onward chemistry

chemical name text :

4-[(4-Azidobutyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione

formula :

C17H18N6O4

formula text :

C17H18N6O4

cas num :

2758431-96-6

USD :

199 USD

product details :

Cereblon ligand with alkyl linker and terminal azide for onward chemistry

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage