7423/10 | Tocris Bioscience 7423/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7423/10

catalog :

7423/10

quantity :

10 mg (also 50 mg)

price :

154 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7423 - INT 131 C21H12Cl4N2O3S CAS No. 315224-26-1

product information

master code :

7423

SKU :

7423/10

product name :

INT 131

unit size :

10 mg (also 50 mg)

description :

PPAR partial agonist

target :

PPAR gamma/NR1C3

category :

Small Molecules

purity :

98%

observed molecular weight :

514.21

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

INT 131 is a potent and selective PPAR partial agonist (EC50 = 4 nM; Ki = 3.7 nM). It has a 20-fold higher affinity for PPAR compared with that of Rosiglitazone (Cat. No. 5325). INT 131 improves glucose tolerance in a rodent model of diabetes without inducing hemodynamic and cardiovascular effects. Antidiabetic agent.

top caption :

PPAR partial agonist

extended description :

PPAR partial agonist

chemical name text :

2,4-Dichloro-N-[3,5-dichloro-4-(3-quinolinyloxy)phenyl]benzenesulfonamide

formula :

C21H12Cl4N2O3S

formula text :

C21H12Cl4N2O3S

cas num :

315224-26-1

USD :

154 USD

product details :

PPAR partial agonist

alt names :

CIMT1, NR1C3, NR1C3GLM1, Nuclear receptor subfamily 1 group C member 3, peroxisome proliferator-activated receptor gamma, peroxisome proliferator-activated receptor gamma 1, PPAR gamma, PPARG, PPARG1peroxisome proliferative activated receptor, gamma, PPARG2PPARgamma, PPAR-gamma

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage