7419/100U | Tocris Bioscience 7419/100U product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7419/100U

catalog :

7419/100U

quantity :

100 ug

price :

328 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7419 - Kyoto Probe-1 C19H13FN2O.CF3CO2H CAS No. 2088021-81-0

product information

master code :

7419

SKU :

7419/100U

product name :

Kyoto Probe-1

unit size :

100 ug

description :

Fluorescent probe that selectively identifies undifferentiated iPS/ES cells

target :

Compounds for ESC/iPSC Proliferation and Renewal

category :

Small Molecules

purity :

95%

observed molecular weight :

418.35

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Kyoto Probe-1 distinguishes between undifferentiated iPS/ES cells and differentiated cells, so may be used for monitoring pluripotency during hESC or iPSC maintenance. Selectivity of labeling is due to ATP-binding cassette transporters ABCB1 and ABCG2 - these mediate efflux of Kyoto Probe-1 and are expressed in differentiated cells, but are repressed in hiPSC and hESC. Kyoto Probe-1 distinguishes between SSEA-4-positive hESCs and human early hematopoietic cells expressing CD45, CD235, CD41a, or CD43 in flow cytometry experiments, making it a valuable tool for studying early hematopoiesis. The product also distinguishes between hiPSCs and hiPSC-derived cardiomyocytes. Note that Kyoto Probe-1 does not differentiate between hiPSCs and differentiated human neuronal stem cells. . Kyoto Probe-1 localizes to the mitochondria in undifferentiated iPS/ES cells only. Suitable in flow cytometry and live cell imaging. . Excitation maximum = 515 nm; emission maximum = 529 nm; Quantum yield = 0.45

top caption :

Fluorescent probe that selectively identifies undifferentiated iPS/ES cells

extended description :

Fluorescent probe that selectively identifies undifferentiated iPS/ES cells

chemical name text :

9-(4-Fluorophenyl)-3-imino-3H-xanthen-6-amine trifluoroacetate

formula :

C19H13FN2O.CF3CO2H

formula text :

C19H13FN2O.CF3CO2H

cas num :

2088021-81-0

USD :

328 USD

product details :

Fluorescent probe that selectively identifies undifferentiated iPS/ES cells

alt names :

KP1

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage