7410/2 | Tocris Bioscience 7410/2 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7410/2

catalog :

7410/2

quantity :

2 mg

price :

258 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7410 - PARPYnD C34H31N9O3 CAS No. 2561483-27-8

product information

master code :

7410

SKU :

7410/2

product name :

PARPYnD

unit size :

2 mg

description :

PARP inhibitor; photoaffinity probe

target :

Poly(ADP-ribose) Polymerase Inhibitors

category :

Small Molecules

purity :

95%

observed molecular weight :

613.68

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PARPYnD is a potent photoaffinity probe (AfBP) for poly(ADP-ribose) polymerase (PARP) (IC50 values for PARP2, PARP1 and PARP6 are 6, 38 and 230 nM, respectively). Can be used to fluorescently label PARP1 and PARP2 in cells when an azide functionalized probe is attached via copper catalysed click-chemistry. PARPYnD enriches recombinant PARP6 spiked into cellular lysates and inhibits PARP6 in cell-free assays; does not label PARP6 in intact cells. Photocrosslinking can be performed by irradiating at 365 nm.

top caption :

PARP inhibitor; photoaffinity probe

extended description :

PARP inhibitor; photoaffinity probe

chemical name text :

3-(3-Butyn-1-yl)-N-[5-cyano-6-[4-[3-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]benzoyl]-1-piperazinyl]-3-pyridinyl]-3H-diazirine-3-propanamide

formula :

C34H31N9O3

formula text :

C34H31N9O3

cas num :

2561483-27-8

USD :

258 USD

product details :

PARP inhibitor; photoaffinity probe

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage