7407/10 | Tocris Bioscience 7407/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7407/10

catalog :

7407/10

quantity :

10 mg

price :

265 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7407 - LEI 401 C24H31N5O2 CAS No. 2393840-15-6

product information

master code :

7407

SKU :

7407/10

product name :

LEI 401

unit size :

10 mg

description :

High affinity N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) inhibitor

target :

Phospholipase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

421.55

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

LEI 401 is a high affinity N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) inhibitor (Ki = 0.027 and 0.18 M for human and mouse NAPE-PLD, respectively; IC50 for human enzyme = 0.86 M). LEI 401 exhibits no significant activity at cannabinoid receptors or other metabolic enzymes of the endocannabinoid system. The product reduces levels of N-acylethanolamines (NAE) in a neuroblastoma cell line in vitro . It also reduces anandamide levels in mouse brain in vivo and impairs fear extinction. LEI 701 is CNS penetrant and cell-permeable.

top caption :

High affinity N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) inhibitor

extended description :

High affinity N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) inhibitor

chemical name text :

N-(Cyclopropylmethyl)-6-[(3S)-3-hydroxy-1-pyrrolidinyl]-2-[(3S)-3-phenyl-1-piperidinyl]-4-pyrimidinecarboxamide

formula :

C24H31N5O2

formula text :

C24H31N5O2

cas num :

2393840-15-6

USD :

265 USD

product details :

High affinity N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage