7377/1 | Tocris Bioscience 7377/1 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7377/1

catalog :

7377/1

quantity :

1 mg (also 10 mg)

price :

218 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Chen L, Hu Y, Wang S, Cao K, Mai W, Sha W, et al. mTOR-neuropeptide Y signaling sensitizes nociceptors to drive neuropathic pain. JCI Insight. 2022;7: pubmed publisher
Sánchez M, Els Heindl S, Beck Sickinger A, Wieneke R, Tampe R. Photoinduced receptor confinement drives ligand-independent GPCR signaling. Science. 2021;371: pubmed publisher

image

image 1 :

Cat.No. 7377 - BIIE 0246 hydrochloride C49H57N11O6.HCl CAS No. 2624332-04-1

product information

master code :

7377

SKU :

7377/1

product name :

BIIE 0246 hydrochloride

unit size :

1 mg (also 10 mg)

description :

Potent, selective and competitive non-peptide NPY Y2 receptor antagonist; active in vivo

target :

NPY Receptor Antagonists

category :

Small Molecules

purity :

98%

observed molecular weight :

968.98

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

BIIE 0246 hydrochloride is a potent, selective and competitive nonpeptide antagonist for the neuropeptide Y Y2 receptor (IC50 = 15 nM). Displays 650-fold selectivity for NPY Y2 over Y1, Y4 and Y5 receptors. Active in vivo .

top caption :

Potent, selective and competitive non-peptide NPY Y2 receptor antagonist; active in vivo

extended description :

Potent, selective and competitive non-peptide NPY Y2 receptor antagonist; active in vivo

chemical name text :

N-[(1S)-4-[(Aminoiminomethyl)amino]-1-[[[2-(3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl)ethyl]amino]carbonyl]butyl]-1-[2-[4-(6,11-dihydro-6-oxo-5H-dibenz[b,e]azepin-11-yl)-1-piperazinyl]-2-oxoethyl]-cyclopentaneacetamide dihydrochloride

formula :

C49H57N11O6.2HCl

formula text :

C49H57N11O6.2HCl

cas num :

246146-31-6

USD :

218 USD

product details :

Potent, selective and competitive non-peptide NPY Y2 receptor antagonist; active in vivo

alt names :

BIIE 0246 2HCl,BIIE0246 2HCl

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage