chemical

7373/2

7373/2

2 mg

463 USD

7373/2

FNIR-Tag, NHS ester

2 mg

Near-infrared (NIR) fluorescent dye (Reactive group: NHS ester) optimized for in vivo imaging

Fluorescent Dyes

Small Molecules

70%

1157.4

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Key information: FNIR-Tag, NHS ester is a near-infrared fluorescent dye; supplied with an NHS ester reactive group for the labeling of primary amines with a high degree of l abeling (DOL). . Application: Designed for in vivo imaging. Also suitable for flow cytometry. . Properties and Photophysical Data: FNIR-Tag, NHS ester provides a higher degree of labeling (DOL) with less aggregation than a leading competitor product when used for antibody conjugation. FNIR-Tag, NHS ester- antibody conjugates exhibit reduced liver uptake in vivo compared with leading competitor conjugates. In addition, FNIR-Tag, NHS ester conjugates are significantly brighter than leading competitor conjugates at similar labeling densities in vivo and in vitro . Antibody conjugation efficiency is greatest at pH 7.4. Excitation and emission maxima ( ) are 766 nM and 788 nM, respectively; quantum yield = 0.099; extinction coefficient = 200,000 M-1cm-1; A280 correction factor = 0.05. . For further information about how FNIR-Tag, NHS ester may be used, please see our protocol: Conjugation Protocol for Amine Reactive Dyes .

Flow cytometry data of FNIR-Tag, NHS in mouse endothelial cells

Near-infrared (NIR) fluorescent dye (Reactive group: NHS ester) optimized for in vivo imaging

2-((E)-2-((E)-2-(3-((4-((2,5-dioxopyrrolidin-1-yl)oxy)-4-oxobutyl)dimethylammonio)propoxy)-3-(2-((E)-1-(2-(2-(2-methoxyethoxy)ethoxy)ethyl)-3,3-dimethyl-5-sulfonatoindolin-2-ylidene)ethylidene)cyclohex-1-en-1-yl)vinyl)-1-(2-(2-(2-methoxyethoxy)ethoxy)ethy

C57H80N4O17S2

C57H80N4O17S2

2365033-54-9

463 USD

Near-infrared (NIR) fluorescent dye (Reactive group: NHS ester) optimized for in vivo imaging

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