7372/10 | Tocris Bioscience 7372/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7372/10

catalog :

7372/10

quantity :

10 mg (also 50 mg)

price :

245 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7372 - CDK8/19i C14H15N5 CAS No. 923596-52-5

product information

master code :

7372

SKU :

7372/10

product name :

CDK8/19i

unit size :

10 mg (also 50 mg)

description :

Potent and selective CDK8 and CDK19 inhibitor; maintains pluripotency of mouse PSCs in culture

target :

Cyclin-dependent Kinase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

253.3

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

CDK8/19i is a potent and selective CDK8 and CDK19 inhibitor (IC50 values are 2.9 and 14.1 nM, respectively). CDK8/19i maintains pluripotency of mouse PSCs in culture. It induces the formation of dome-shaped colonies and upregulates Nanog -GFP reporter and endogenous Nanog expression in mouse ESCs in vitro .

top caption :

Potent and selective CDK8 and CDK19 inhibitor; maintains pluripotency of mouse PSCs in culture

extended description :

Potent and selective CDK8 and CDK19 inhibitor; maintains pluripotency of mouse PSCs in culture

chemical name text :

N-Propyl-3-(4-pyridinyl)imidazo[1,2-b]pyridazin-6-amine

formula :

C14H15N5

formula text :

C14H15N5

cas num :

923596-52-5

USD :

245 USD

product details :

Potent and selective CDK8 and CDK19 inhibitor; maintains pluripotency of mouse PSCs in culture

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage