7352/1 | Tocris Bioscience 7352/1 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7352/1

catalog :

7352/1

quantity :

1 mg

price :

506 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7352 - YM 254890 C46H69N7O15 CAS No. 568580-02-9

product information

master code :

7352

SKU :

7352/1

product name :

YM 254890

unit size :

1 mg

description :

G -protein inhibitor; potent inhibitor of Gq/11 signaling

target :

GTPase Inhibitors

category :

Small Molecules

purity :

95%

observed molecular weight :

960.09

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

YM 254890 is a G -protein inhibitor. Potently inhibits Gq/11 heterotrimeric G protein signaling. Inhibits ATP/UTP-induced Ca2+ increase in HCAE cells expressing P2Y2 receptor (IC50 = 50 nM); carbachol-induced production of IP1 in CHO cells expressing M1 receptor (IC50 = 95 nM); and ADP-induced Ca2+ increase in platelets, in vitro (IC50 = 2 M). Also inhibits Gs-induced cAMP elevation and G protein-coupled MAPK/ERK signaling.

top caption :

G -protein inhibitor; potent inhibitor of Gq/11 signaling

extended description :

G -protein inhibitor; potent inhibitor of Gq/11 signaling

chemical name text :

(R)-1-((3S,6S,9S,12S,18R,21S,22R)-21-acetamido-18-benzyl-3-((R)-1-methoxyethyl)-4,9,10,12,16,22-hexamethyl-15-methylene-2,5,8,11,14,17,20-heptaoxo-1,19-dioxa-4,7,10,13,16-pentaazacyclodocosan-6-yl)-2-methylpropyl (2S,3R)-2-acetamido-3-hydroxy-4-methylpent

formula :

C46H69N7O15

formula text :

C46H69N7O15

cas num :

568580-02-9

USD :

506 USD

product details :

G -protein inhibitor; potent inhibitor of Gq/11 signaling

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage