7343/10 | Tocris Bioscience 7343/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7343/10

catalog :

7343/10

quantity :

10 mg (also 50 mg)

price :

251 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7343 - Laropiprant C21H19ClFNO4S CAS No. 571170-77-9

product information

master code :

7343

SKU :

7343/10

product name :

Laropiprant

unit size :

10 mg (also 50 mg)

description :

Potent and selective prostaglandin D2 receptor antagonist

target :

Prostanoid Receptor Antagonists

category :

Small Molecules

purity :

98%

observed molecular weight :

435.9

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Laropiprant is a potent and selective prostaglandin D2 receptor antagonist (IC50 = 0.09 nM in washed platelets; Ki = 0.57). It exhibits selectivity for binding to PGD2 receptors over other prostanoid receptors (Ki values are 2.95 nM for TP, EP1, EP2, EP3, EP4, FP and IP). Laropiprant promotes coagulation of whole blood ex vivo and reduces bleeding time in mice in vivo . In a mouse model of intracerebral hemorrhage, Laropiprant reduces lesion volume and attenuates neurological deficit scores. The compound also reduces Niacin (Cat. No. 4106) induced vasodilation.

top caption :

Potent and selective prostaglandin D2 receptor antagonist

extended description :

Potent and selective prostaglandin D2 receptor antagonist

chemical name text :

(3R)-4-[(4-Chlorophenyl)methyl]-7-fluoro-1,2,3,4-tetrahydro-5-(methylsulfonyl)cyclopent[b]indole-3-acetic acid

formula :

C21H19ClFNO4S

formula text :

C21H19ClFNO4S

cas num :

571170-77-9

USD :

251 USD

product details :

Potent and selective prostaglandin D2 receptor antagonist

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage