7342/50 | Tocris Bioscience 7342/50 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7342/50

catalog :

7342/50

quantity :

50 mg

price :

133 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7342 - Emetine dihydrochloride C29H40N2O4.2HCl CAS No. 316-42-7

product information

master code :

7342

SKU :

7342/50

product name :

Emetine dihydrochloride

unit size :

50 mg

description :

RNA polymerase inhibitor; inhibits replication of a broad range of RNA and DNA viruses, including SARS-CoV-2 and Zika

target :

RNA/DNA Polymerase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

553.57

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Emetine is a RNA polymerase inhibitor. It inhibits SARS-CoV-2 replication (EC50 = 460 nM) and in combination with Remdesivir (Cat. No.7226) synergistically inhibits the viral yield of SARS-CoV-2 by 64.9%. Emetine attenuates hCoV-OC43, hCoV-NL43, SARS-CoV, MERS-CoV, and MHV-A59 in vitro with EC50 values in the low micromolar range. It also inhibits replication of a broad range of RNA and DNA viruses, including influenza, ebolavirus and HIV-1. Emetine potently inhibits ZIKV replication in vitro (IC50 = 52.9 nm) and suppresses ZIKV viral load in vivo . Anti-inflammatory, antiviral, antimalarial, antibacterial and anti-amebic.

top caption :

RNA polymerase inhibitor; inhibits replication of a broad range of RNA and DNA viruses, including SARS-CoV-2 and Zika

extended description :

RNA polymerase inhibitor; inhibits replication of a broad range of RNA and DNA viruses, including SARS-CoV-2 and Zika

chemical name text :

(2S,3R,11bS)-3-Ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-isoquinolinyl]methyl]-2H-benzo[a]quinolizine dihydrochloride

formula :

C29H40N2O4.2HCl

formula text :

C29H40N2O4.2HCl

cas num :

316-42-7

USD :

133 USD

product details :

RNA polymerase inhibitor; inhibits replication of a broad range of RNA and DNA viruses, including SARS-CoV-2 and Zika

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage