7339/10 | Tocris Bioscience 7339/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7339/10

catalog :

7339/10

quantity :

10 mg (also 50 mg)

price :

109 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7339 - RIPA 56 C13H19NO2 CAS No. 1956370-21-0

product information

master code :

7339

SKU :

7339/10

product name :

RIPA 56

unit size :

10 mg (also 50 mg)

description :

Potent and metabolically stable RIP1 kinase inhibitor

target :

RIP Kinase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

221.3

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

RIPA 56 is a potent and metabolically stable receptor-interacting protein kinase 1 (RIPK1) inhibitor (EC50 = 13 nM). RIPA-56 shows no inhibition of RIP3 kinase at 10 M . RIPA 56 blocks necroptosis and aging of the mouse male reproductive system. RIPA 56 reduces tumor necrosis factor (TNF )-induced mortality and multi-organ damage in a mouse model of systemic inflammatory response syndrome (SIRS). RIPA 56 is orally bioavailable.

top caption :

Potent and metabolically stable RIP1 kinase inhibitor

extended description :

Potent and metabolically stable RIP1 kinase inhibitor

chemical name text :

N-Hydroxy-2,2-dimethyl-N-(phenylmethyl)butanamide

formula :

C13H19NO2

formula text :

C13H19NO2

cas num :

1956370-21-0

USD :

109 USD

product details :

Potent and metabolically stable RIP1 kinase inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage