7336/10 | Tocris Bioscience 7336/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7336/10

catalog :

7336/10

quantity :

10 mg (also 50 mg)

price :

175 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7336 - Dinaciclib C21H28N6O2 CAS No. 779353-01-4

product information

master code :

7336

SKU :

7336/10

product name :

Dinaciclib

unit size :

10 mg (also 50 mg)

description :

Potent and selective inhibitor of CDK2, CDK5, CDK1 and CDK9

target :

Cyclin-dependent Kinase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

396.5

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Dinaciclib is a potent and selective inhibitor of CDK2, CDK5, CDK1 and CDK9 activity in vitro (IC50 values are 1, 1, 3 and 4 nM, respectively). The compound inhibits DNA replication by blocking thymidine DNA incorporation in A2780 cells (IC50 = 4 nM). Dinaciclib induces regression of established solid tumors in mouse models and shows antiviral activity against SARS-CoV-2 in vitro (Vero E6, IC50 = 0.127 A549-ACE2, IC50 = 0.032 M).

top caption :

Potent and selective inhibitor of CDK2, CDK5, CDK1 and CDK9

extended description :

Potent and selective inhibitor of CDK2, CDK5, CDK1 and CDK9

chemical name text :

(2S)-1-[3-Ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-2-piperidineethanol

formula :

C21H28N6O2

formula text :

C21H28N6O2

cas num :

779353-01-4

USD :

175 USD

product details :

Potent and selective inhibitor of CDK2, CDK5, CDK1 and CDK9

alt names :

SCH 727965

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage