7310/5 | Tocris Bioscience 7310/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7310/5

catalog :

7310/5

quantity :

5 mg (also 25 mg)

price :

165 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7310 - Emricasan C26H27F4N3O7 CAS No. 254750-02-2

product information

master code :

7310

SKU :

7310/5

product name :

Emricasan

unit size :

5 mg (also 25 mg)

description :

Potent pan-caspase inhibitor

target :

Caspase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

569.51

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Emricasan is a potent caspase inhibitor (IC50 values are 0.3, 0.4, 2, 4, 6, 6 and 20 nM for caspase-9, -1, -3, -6, -7, -8, and -2, respectively). Emricasan is antiapoptotic by inhibiting caspase 8. It also preserves cell viability after infection with several strains of Zika. Emricasan promotes survival of pluripotent stem cells in culture when used in combination with Chroman-1 (Cat. No. 7163), trans-ISRIB (Cat. No. 5284) and Polyamine Supplement x1000 (lyophilized) (Cat. No. 7739), a combination known as CEPT. When used as part of the CEPT cocktail, Emricasan improves survival of differentiated cells following cryopreservation. The compound also reduces hepatic inflammation in an animal model of liver injury. Orally bioavailable.

top caption :

Potent pan-caspase inhibitor

extended description :

Potent pan-caspase inhibitor

chemical name text :

N-[2-(1,1-Dimethylethyl)phenyl]-2-oxoglycyl-N-[(1S)-1-(carboxymethyl)-2-oxo-3-(2,3,5,6-tetrafluorophenoxy)propyl]-L-alaninamide

formula :

C26H27F4N3O7

formula text :

C26H27F4N3O7

cas num :

254750-02-2

USD :

165 USD

product details :

Potent pan-caspase inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage