7309/10 | Tocris Bioscience 7309/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7309/10

catalog :

7309/10

quantity :

10 mg (also 50 mg)

price :

74 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7309 - Vemurafenib C23H18ClF2N3O3S CAS No. 918504-65-1

product information

master code :

7309

SKU :

7309/10

product name :

Vemurafenib

unit size :

10 mg (also 50 mg)

description :

Potent BRAF and CRAF inhibitor

target :

Raf Kinase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

489.92

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Vemurafenib is a potent inhibitor of BRAFV600E, C-Raf and wild type B-Raf (IC50 values are 13-31 nM, 6.7-48 nM and 100-160 nM, respectively. Vemurafenib also inhibits SRMS, ACK1 KHS1, FGR (IC50 values are 18 nM, 19 nM, 51 nM and 63 nM, respectively). Vemurafenib shows antitumor activity and induces autophagy in BRAF-mutant thyroid cancer cells.

top caption :

Potent BRAF and CRAF inhibitor

extended description :

Potent BRAF and CRAF inhibitor

chemical name text :

N-[3-[[5-(4-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide

formula :

C23H18ClF2N3O3S

formula text :

C23H18ClF2N3O3S

cas num :

918504-65-1

USD :

74 USD

product details :

Potent BRAF and CRAF inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage