7304/2 | Tocris Bioscience 7304/2 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7304/2

catalog :

7304/2

quantity :

2 mg

price :

595 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7304 - JH-XI-10-02 C53H69N5O9 CAS No. 2209085-22-1

product information

master code :

7304

SKU :

7304/2

product name :

JH-XI-10-02

unit size :

2 mg

description :

CDK8 Degrader (PROTAC )

target :

Active Degraders

category :

Small Molecules

purity :

98%

observed molecular weight :

920.16

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

JH-XI-10-02 is a CDK8 Degrader (PROTAC ) comprising the cereblon binding ligand Pomalidomide (Cat. No. 6302) joined by a linker to a CDK8 inhibitor. JH-XI-10-02 (1 M) induces significant proteasome-dependent degradation of CDK8 in Jurkat cells after 24 h, with no significant effect on CDK19 levels. . CDK8 antibody validated for Western Blot also available: Catalog # NBP2-92972 .

top caption :

CDK8 Degrader (PROTAC )

extended description :

CDK8 Degrader (PROTAC )

chemical name text :

15-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-N-[(3 ,5 ,17 )-17-(7-isoquinolinyl)androstan-3-yl]-N-methyl-4,7,10,13-tetraoxapentadecanamide

formula :

C53H69N5O9

formula text :

C53H69N5O9

cas num :

2209085-22-1

USD :

595 USD

product details :

CDK8 Degrader (PROTAC )

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage