Famotidine | Tocris Bioscience 7290 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Famotidine

catalog :

7290

quantity :

100 mg

price :

65 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7290 - Famotidine C8H15N7O2S3 CAS No. 76824-35-6

product information

brand :

Tocris

master code :

7290

SKU :

7290/100

product name :

Famotidine

description :

Potent and high affinity H2 biased inverse agonist

target :

Histamine H2 Receptor Antagonists

category :

Small Molecules

unit size :

100 mg

purity :

98%

observed molecular weight :

337.44

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and high affinity histamine H2 receptor biased inverse agonist (Kd = 14 nM, IC50 = 33 nM). Reduces basal receptor activity by 75%. Inhibits Gs-mediated pathways but acts as a partial agonist of -arrestin recruitment (EC50 = 105 nM). Inhibits gastric acid secretion and histamine-induced mast cell activation. Also inhibits HIV replication in vitro .

catalog number base :

7290

product keywords :

YM 11170 MK 208 histamine h2 receptor inverse agonists antagonists biased signaling antiviral COVID-19 mast cell activation Histamine H2 Receptors COVID-19 HIV 7290,

extended description :

Potent and high affinity H2 biased inverse agonist

chemical name text :

3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N-(aminosulfonyl)propanimidamide

formula :

C 8 H 15 N 7 O 2 S 3

formula text :

C8H15N7O2S3

cas num :

76824-35-6

2020 USD :

2021 USD :

65 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage