7280/5 | Tocris Bioscience 7280/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7280/5

catalog :

7280/5

quantity :

5 mg (also 25 mg)

price :

182 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7280 - GRL 0617 C20H20N2O CAS No. 1093070-16-6

product information

master code :

7280

SKU :

7280/5

product name :

GRL 0617

unit size :

5 mg (also 25 mg)

description :

Coronavirus PLpro inhibitor

target :

Papain-like Protease Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

304.39

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

GRL 0617 is a coronavirus papain-like protease (Plpro) inhibitor (IC50 values are 0.6 and 0.8 M for SARS-COV and SARS-CoV-2 PLpro, respectively). Inhibits deubiquitination activity of SARS-CoV PLpro. Displays no inhibition of human deubiquitinating enzymes. Improves cell viability following SARS-CoV infection. Inhibits SARS-CoV-2 viral replication and induces antiviral immune signaling pathways following SARS-CoV-2 infection in CaCo-2 cells.

top caption :

Coronavirus PLpro inhibitor

extended description :

Coronavirus PLpro inhibitor

chemical name text :

5-Amino-2-methyl-N-[(1R)-1-(1-naphthalenyl)ethyl]benzamide

formula :

C20H20N2O

formula text :

C20H20N2O

cas num :

1093070-16-6

USD :

182 USD

product details :

Coronavirus PLpro inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage