iP300w | Tocris Bioscience 7270 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

iP300w

catalog :

7270

quantity :

5 mg

price :

295 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7270 - iP300w C29H27F5N6O4

product information

brand :

Tocris

master code :

7270

SKU :

7270/5

product name :

iP300w

description :

Potent p300/CBP inhibitor

target :

Histone Acetyltransferase Inhibitors

category :

Small Molecules

unit size :

5 mg

purity :

98%

observed molecular weight :

618.55

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent p300/CBP inhibitor. Inhibits p300-mediated H3K9 acetylation (IC50 = 33 nM). Inhibits cytotoxicity of DUX4 and overexpression of DUX4 target genes in vitro . Also impairs DUX4-mediated transcription in an animal model of facioscapulohumeral muscular dystrophy (FSHD).

catalog number base :

7270

product keywords :

HAT inhibitors inhibits Histone Acetyltransferases KAT Lysine Aceyltransferases p300 CBP Histone Acetyltransferases 7270,

extended description :

Potent p300/CBP inhibitor

chemical name text :

2-[3 -Fluoro-5 -[1-[2-(methylamino)-2-oxoethyl]-1H-pyrazol-4-yl]-2,5-dioxo-2 ,3 -dihydrospiro(imidazolidine-4,1 -inden)-1-yl]-N-(4-fluorobenzyl)-N-(1,1,1-trifluoropropane-2-yl)acetamide

formula :

C 29 H 27 F 5 N 6 O 4

formula text :

C29H27F5N6O4

2020 USD :

295

2021 USD :

295 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage