7268/5 | Tocris Bioscience 7268/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7268/5

catalog :

7268/5

quantity :

5 mg

price :

304 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7268 - SJFaSJFalphaSJFalpha C59H67F2N7O11S CAS No. 2254609-27-1

product information

master code :

7268

SKU :

7268/5

product name :

SJFa SJFalpha SJFalpha

unit size :

5 mg

description :

Potent and selective p38 PROTAC

target :

Active Degraders

category :

Small Molecules

purity :

98%

observed molecular weight :

1120.28

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

SJF is a potent and selective p38 PROTAC Degrader (DC50 = 7.16 nM; Dmax = 97.4%). SJF comprises the multikinase inhibitor foretinib joined by a linker to a VHL ligand. Displays significantly lower potency degradation at p38 (DC50 = 299 nM). Exhibits no significant degradation of p38 , p38 or related MAPKs, ERK1/2, or JNK1/2. . p38 antibodies validated for Simple Western (automated Western) instruments also available: Catalog # AF1347 and MAB1347 . . PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license .

top caption :

Potent and selective p38 PROTAC

extended description :

Potent and selective p38 PROTAC

chemical name text :

N-(3-Fluoro-4-((7-(4-(4-(2-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-2-oxoethoxy)butoxy)butoxy)-6-methoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarb

formula :

C59H67F2N7O11S

formula text :

C59H67F2N7O11S

cas num :

2254609-27-1

USD :

304 USD

product details :

Potent and selective p38 PROTAC

alt names :

SJFa PROTAC,SJFalpha PROTAC,SJF PROTAC

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage