7267/5 | Tocris Bioscience 7267/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7267/5

catalog :

7267/5

quantity :

5 mg

price :

420 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7267 - SJFd C62H63F2N7O12S CAS No. 2254609-23-7

product information

master code :

7267

SKU :

7267/5

product name :

SJFd

unit size :

5 mg

description :

Potent and selective p38 PROTAC

target :

Active Degraders

category :

Small Molecules

purity :

98%

observed molecular weight :

1168.28

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

SJF is a potent and selective PROTAC Degrader of p38 (DC50 = 46.17 nM; Dmax = 99.41%). SJF comprises the multikinase inhibitor foretinib joined by a linker to a VHL ligand. Exhibits no significant degradation of p38 , or . Selectively degrades p38 in MDA-MB-231 cells. . PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license .

top caption :

Potent and selective p38 PROTAC

extended description :

Potent and selective p38 PROTAC

chemical name text :

N-(3-Fluoro-4-((7-(2-(2-(2-(2-(((2S,4R)-4-hydroxy-1-((S)-3-methyl-2-(1-oxoisoindolin-2-yl)butanoyl)pyrrolidine-2-carboxamido)methyl)-5-(4-methylthiazol-5-yl)phenoxy)ethoxy)ethoxy)ethoxy)-6-methoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,

formula :

C62H63F2N7O12S

formula text :

C62H63F2N7O12S

cas num :

2254609-23-7

USD :

420 USD

product details :

Potent and selective p38 PROTAC

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage