7265/5 | Tocris Bioscience 7265/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7265/5

catalog :

7265/5

quantity :

5 mg

price :

243 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7265 - GMB 475 C43H46F3N7O7S CAS No. 2490599-18-1

product information

master code :

7265

SKU :

7265/5

product name :

GMB 475

unit size :

5 mg

description :

BCR-ABL1 kinase PROTAC Degrader

target :

Active Degraders

category :

Small Molecules

purity :

98%

observed molecular weight :

861.94

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

GMB 475 is a BCR-ABL1 kinase PROTAC Degrader. Induces degradation of BCR-ABL1 and cABL1, inhibits downstream STAT5 signaling and suppresses cell proliferation in chronic myeloid leukemia cells lines. . PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license .

top caption :

BCR-ABL1 kinase PROTAC

extended description :

BCR-ABL1 kinase PROTAC Degrader

chemical name text :

(2S,4R)-1-((S)-3,3-Dimethyl-2-(2-(2-(4-(6-((4-(trifluoromethoxy)phenyl)amino)pyrimidin-4-yl)phenoxy)ethoxy)acetamido)butanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide

formula :

C43H46F3N7O7S

formula text :

C43H46F3N7O7S

cas num :

2490599-18-1

USD :

243 USD

product details :

BCR-ABL1 kinase PROTAC Degrader

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage