SJF 1521 | Tocris Bioscience 7261 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SJF 1521

catalog :

7261

quantity :

5 mg

price :

345 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7261 - SJF 1521 C57H61ClFN7O9S CAS No. 2230821-40-4

product information

brand :

Tocris

master code :

7261

SKU :

7261/5

product name :

SJF 1521

description :

Selective EGFR Degrader

target :

Active Degraders

category :

Small Molecules

unit size :

5 mg

purity :

98%

observed molecular weight :

1074.66

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective EGFR Degrader. Comprises the EGFR inhibitor lapatinib (Cat. No. 6811) joined by a linker to a von Hippel-Lindau (VHL) recruiting ligand. Exhibits selectivity for EGFR, including mutant forms, over HER2. Induces degradation of EGFR in OVCAR8 cells.

catalog number base :

7261

product keywords :

SJF1521 protac active degraders degrades selective EGFR epidermal growth factor receptor ERBB von Hippel Lindau VHL E3 ligases targeted protein degradation TPD protac protacs Active Degraders EGFR 7261, target protein knockdown, PROTAC, SNIPER

extended description :

Selective EGFR Degrader

chemical name text :

(2S,4R)-1-((S)-2-(tert-Butyl)-14-(4-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)phenoxy)-4-oxo-6,9,12-trioxa-3-azatetradecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide

formula :

C 57 H 61 ClFN 7 O 9 S

formula text :

C57H61ClFN7O9S

cas num :

2230821-40-4

2020 USD :

345

2021 USD :

345 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage