7261/5 | Tocris Bioscience 7261/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7261/5

catalog :

7261/5

quantity :

5 mg

price :

420 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7261 - SJF 1521 C57H61ClFN7O9S CAS No. 2230821-40-4

product information

master code :

7261

SKU :

7261/5

product name :

SJF 1521

unit size :

5 mg

description :

Selective EGFR PROTAC Degrader

target :

Active Degraders

category :

Small Molecules

purity :

98%

observed molecular weight :

1074.66

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

SJF 1521 is a selective EGFR PROTAC Degrader. SJF 1521 comprises the EGFR inhibitor lapatinib (Cat. No. 6811) joined by a linker to a von Hippel-Lindau (VHL) recruiting ligand. Exhibits selectivity for EGFR, including mutant forms, over HER2. Induces degradation of EGFR in OVCAR8 cells. . EGFR antibody validated for Simple Western (automated Western) instruments and Western Blot also available: Catalog # AF231 . PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license .

top caption :

Selective EGFR PROTAC

extended description :

Selective EGFR PROTAC Degrader

chemical name text :

(2S,4R)-1-((S)-2-(tert-Butyl)-14-(4-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)phenoxy)-4-oxo-6,9,12-trioxa-3-azatetradecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide

formula :

C57H61ClFN7O9S

formula text :

C57H61ClFN7O9S

cas num :

2230821-40-4

USD :

420 USD

product details :

Selective EGFR PROTAC Degrader

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage