7230/5 | Tocris Bioscience 7230/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7230/5

catalog :

7230/5

quantity :

5 mg (also 25 mg)

price :

176 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Franko N, Teixeira A, Xue S, Charpin El Hamri G, Fussenegger M. Design of modular autoproteolytic gene switches responsive to anti-coronavirus drug candidates. Nat Commun. 2021;12:6786 pubmed publisher

image

image 1 :

Cat.No. 7230 - MPro N3 C35H48N6O8 CAS No. 884650-98-0

product information

master code :

7230

SKU :

7230/5

product name :

MPro N3

unit size :

5 mg (also 25 mg)

description :

Coronavirus Mpro inhibitor

target :

3C and 3CL Protease Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

680.8

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

MPro N3 is a coronavirus main protease (Mpro) inhibitor (respective IC50 values are 2.7, 4 and 8.8 M for MHV-A29, HCoV-229E and FOPV replication in vitro ). Inhibits viral cell infection in an MHV plaque reduction assay. Also inhibits SARS-CoV-2 viral cell entry in a plaque reduction assay (IC50 = 16.8 M).

top caption :

Coronavirus Mpro inhibitor

extended description :

Coronavirus Mpro inhibitor

chemical name text :

N-[(5-Methyl-3-isoxazolyl)carbonyl]-L-alanyl-L-valyl-N-[(1S,2E)-4-oxo-1-[[(3S)-2-oxo-3-pyrrolidinyl]methyl]-4-(phenylmethoxy)-2-buten-1-yl]-L-leucinamide

formula :

C35H48N6O8

formula text :

C35H48N6O8

cas num :

884650-98-0

USD :

176 USD

product details :

Coronavirus Mpro inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage