chemical

7227/10

7227/10

10 mg (also 50 mg)

164 USD

7227/10

GS 441524

10 mg (also 50 mg)

Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleotide

RNA/DNA Polymerase Inhibitors

Small Molecules

98%

291.27

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GS 441524 is a viral RNA-dependent RNA polymerase (RdRp) inhibitor and broad spectrum antiviral nucleotide; active metabolite of Remdesivir (Cat. No. 7226). Competes with natural nucleoside triphosphates, blocking viral RNA synthesis. Exhibits antiviral activity against viruses from Coronaviridae family including SARS-CoV-2 in vitro , and SARS-CoV and feline infectious peritonitis virus (FIPV) in vitro and in vivo . Inhibits SARS-CoV and MERS-CoV- infected HAE cultures (EC50 values are 0.18 and 0.86 M, respectively) and inhibits murine hepatitis virus (MHV) (EC50 = 1.1 M).

Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleotide

Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleotide

(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile

C12H13N5O4

C12H13N5O4

1191237-69-0

164 USD

Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleotide

Store at -20░C