7226/10 | Tocris Bioscience 7226/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7226/10

catalog :

7226/10

quantity :

10 mg (also 50 mg)

price :

168 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Kim D, Weller B, Lin C, Sheykhkarimli D, Knapp J, Dugied G, et al. A proteome-scale map of the SARS-CoV-2-human contactome. Nat Biotechnol. 2023;41:140-149 pubmed publisher
Coffin A, Dale E, Doppenberg E, Fearington F, Hayward T, Hill J, et al. Putative COVID-19 therapies imatinib, lopinavir, ritonavir, and ivermectin cause hair cell damage: A targeted screen in the zebrafish lateral line. Front Cell Neurosci. 2022;16:941031 pubmed publisher

image

image 1 :

Cat.No. 7226 - Remdesivir C27H35N6O8P CAS No. 1809249-37-3

product information

master code :

7226

SKU :

7226/10

product name :

Remdesivir

unit size :

10 mg (also 50 mg)

description :

Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleotide prodrug

target :

RNA/DNA Polymerase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

602.58

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Remdesivir is a viral RNA-dependent RNA polymerase inhibitor (RdRp) and broad spectrum antiviral nucleotide prodrug. Metabolized to active form, GS 441524 (Cat. No. 7227). Exhibits activity against a range of RNA viruses in vitro (EC50 values are 0.019, 0.07, 0.07 - 0.34, 0.086 - 0.14, and 23.15 M against RSV, SARS-CoV, MERS-CoV, EBOV and SARS-CoV-2, respectively). Exhibits antiviral efficacy in animal models of MERS-CoV and EBOV infection.

top caption :

Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleotide prodrug

extended description :

Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleotide prodrug

chemical name text :

2-Ethylbutyl (2S)-2-[[(S)-[[(2R,3S,4R,5R)-5-(4-aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl]methoxy]phenoxyphosphoryl]amino]propanoate

formula :

C27H35N6O8P

formula text :

C27H35N6O8P

cas num :

1809249-37-3

USD :

168 USD

product details :

Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleotide prodrug

alt names :

GS-5734

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage