7219/5 | Tocris Bioscience 7219/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7219/5

catalog :

7219/5

quantity :

5 mg

price :

425 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7219 - CRBN PROTAC 14a C53H72N8O13S CAS No. 2358775-70-7

product information

master code :

7219

SKU :

7219/5

product name :

CRBN PROTAC 14a

unit size :

5 mg

description :

Cereblon Degrader (PROTAC )

target :

Active Degraders

category :

Small Molecules

purity :

98%

observed molecular weight :

1061.26

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

CRBN PROTAC 14a is a cereblon Degrader (PROTAC ). Comprises a ligand for Von Hippel Lindau (VHL) protein joined by a linker to a cereblon targeting ligand. Preferentially degrades cereblon (DC50 = 200 nM in HEK293 cells). Induces rapid and profound cereblon degradation (98% decrease after 8 h at 1 M in HEK293 cells). . CRBN antibody validated for Simple Western (automated Western) instruments and Western Blot also available: Catalog # NBP1-91810 . . PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license .

top caption :

Cereblon Degrader (PROTAC )

extended description :

Cereblon Degrader (PROTAC )

chemical name text :

N1-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethyl)-N20-((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)-3,9,12,18-tetraoxaicosanediamide

formula :

C53H72N8O13S

formula text :

C53H72N8O13S

cas num :

2358775-70-7

USD :

425 USD

product details :

Cereblon Degrader (PROTAC )

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage